Director of Operations Job at McKesson, O Fallon, MO

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  • McKesson
  • O Fallon, MO

Job Description

McKesson is an impact-driven, Fortune 10 company that touches virtually every aspect of healthcare. We are known for delivering insights, products, and services that make quality care more accessible and affordable. Here, we focus on the health, happiness, and well-being of you and those we serve – we care.

What you do at McKesson matters. We foster a culture where you can grow, make an impact, and are empowered to bring new ideas. Together, we thrive as we shape the future of health for patients, our communities, and our people. If you want to be part of tomorrow’s health today, we want to hear from you.

McKesson’s St. Louis Distribution Center is seeking a Director of Operations to lead all aspects of facility performance, including operational execution, financial accountability, inventory management, and long-term strategic planning.

This role is responsible for creating a high-performing environment focused on safety, quality, productivity, and employee engagement — all in service of delivering exceptional customer experiences.

Key Responsibilities

Strategic & Cross-Functional Leadership

  • Align local operations with regional and enterprise-wide strategic initiatives.
  • Set priorities, allocate resources, and ensure teams are working toward shared goals.
  • Partner with Sales, HR, Engineering, Six Sigma, Finance, and Transportation to drive performance and customer satisfaction.
  • Stay ahead of industry trends, customer needs, and labor planning challenges.

People Leadership

  • Lead and develop a team of up to 10 DC leaders and 100+ employees.
  • Foster a culture of accountability, collaboration, and continuous improvement.
  • Model McKesson’s ICARE and ILEAD values in all interactions.
  • Drive employee engagement, talent development, and succession planning.
  • Address workforce challenges including turnover, generational dynamics, and DEI initiatives.

Financial Ownership

  • Own P&L performance, budgeting, and expense control for the facility.
  • Monitor and analyze operational metrics to support cost-effective decision-making.
  • Ensure inventory accuracy and minimize exposure to risk and loss.

Compliance & Safety

  • Ensure compliance with federal, state, local, and company regulations (DEA, FDA, OSHA).
  • Lead internal audits and ensure SOP adherence across operations.
  • Champion a culture of safety through training, monitoring, and proactive risk mitigation.

Minimum Qualifications

  • 12+ years of professional experience, including 4+ years in a management role
  • Bachelor’s degree in a related field or equivalent experience

Critical Skills

  • Ability to manage multiple priorities and navigate complex decision-making environments
  • Strong organizational, communication, and negotiation skills
  • Experience with WMS systems, warehouse control systems, and material handling equipment
  • Deep understanding of drug distribution and wholesaling across customer segments
  • Proficiency in Microsoft Office and McKesson’s suite of PC-based applications
  • Proven success in building and developing high-performing teams

Additional Skills & Attributes

  • HR leadership and talent development
  • Results orientation and energy
  • Decisiveness and sound judgment
  • Openness, candor, and customer focus
  • Business process improvement mindset
  • Commitment to diversity and inclusion

Working Conditions

  • Office and warehouse environment
  • Flexibility to work various hours across a 24-hour operational schedule

Why McKesson? We’re shaping the future of healthcare through innovation, integrity, and a shared commitment to better outcomes. Join us and lead with purpose, impact, and a passion for powering better health.

McKesson is an Equal Opportunity/Affirmative Action employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, creed, sex, sexual orientation, gender identity, national origin, disability, or protected veteran status. Qualified applicants will not be disqualified based on criminal history.

If you need a reasonable accommodation to assist with your job search or application, please contact: McKessonTalentAcquisition@mckesson.com. (Note: Resumes or CVs submitted to this email will not be accepted.)

We are proud to offer a competitive compensation package at McKesson as part of our Total Rewards. This is determined by several factors, including performance, experience and skills, equity, regular job market evaluations, and geographical markets. The pay range shown below is aligned with McKesson's pay philosophy, and pay will always be compliant with any applicable regulations. In addition to base pay, other compensation, such as an annual bonus or long-term incentive opportunities may be offered. For more information regarding benefits at McKesson, please click here.

Our Base Pay Range for this position

$111,200 - $185,300

McKesson is an Equal Opportunity Employer

McKesson provides equal employment opportunities to applicants and employees and is committed to a diverse and inclusive environment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability, age or genetic information. For additional information on McKesson’s full Equal Employment Opportunity policies, visit our Equal Employment Opportunity page.

Join us at McKesson!

Job Tags

Full time, Work at office, Local area,

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